Premier League
5th tour
Arsenal
21 September
11:30
(EDT)
Manchester City

Arsenal vs Manchester City: prediction & betting odds September 21, 2025

The Premier League Matchday 5 clash between Arsenal and Manchester City will take place on September 21 at the Emirates Stadium in London. Arsenal vs. Manchester City: prediction and betting odds, statistics.

Arsenal

The Gunners have accumulated 9 points, placing them second in the standings behind Liverpool. The team lost to the league leaders in the third round (0-1). In the other matches, the Londoners secured victories with clean sheets: they thrashed Leeds at home (5-0) and Nottingham Forest (3-0), and defeated Manchester United away (1-0). It's also worth noting that Mikel Arteta's side has avoided defeat in 6 of their last 7 Premier League encounters (5 wins and 1 draw).

  • No more than 3 goals have been scored in 5 of Arsenal's last 6 Premier League games.
  • The Gunners have not lost in 7 of their last 8 home league matches (5 wins and 2 draws).
  • Arsenal has conceded just 1 goal in the first half of their last 8 home games in the Premier League.

Predicted lineup for Arsenal (4-3-3)

David Raya – Gabriel Magalhães, Jurrien Timber, Cristian Mosquera, Riccardo Calafiori – Martin Zubimendi, Martin Ødegaard, Mikel Merino – Eberechi Eze, Noni Madueke, Viktor Gyökeres.

Forwards Bukayo Saka, Kai Havertz, and Gabriel Jesus will miss the upcoming matches due to injuries. The participation of midfielder Martin Ødegaard and defender William Saliba is in doubt.

Manchester City

The Citizens have been inconsistent so far, collecting only 6 points from 4 rounds, placing them in a modest 8th position. After a convincing victory over Wolverhampton (4-0), the club unexpectedly lost to Tottenham (0-2) and Brighton (1-2). However, in their last match, the team thrashed Manchester United, defeating their city rivals 3-0.

  • The Citizens have not lost in 12 of their last 14 league matches (9 wins and 3 draws).
  • At least one team failed to score in 6 of Manchester City's last 8 Premier League games.
  • The Mancunians have kept clean sheets in 5 of their last 6 away Premier League matches.

Predicted lineup for Manchester City (3-5-2)

Gianluigi Donnarumma – Abdukodir Khusanov, Ruben Dias, Josko Gvardiol – Nico O'Reilly, Tijjani Reijnders, Rodri Hernandez, Bernardo Silva, Phil Foden – Jeremy Doku, Erling Haaland.

Due to injuries, goalkeeper Marcus Bettinelli, defender Rayan Aït-Nouri, midfielder Mateo Kovačić, and forward Rayan Cherki will miss the match. The participation of defender John Stones is questionable.

Referee

Stuart Attwell (England)

Matches – 22 (Premier League, 2024/25–2025/26);

Yellow cards shown (including second yellows) – 93;

Average yellow cards per match – 4.2;

Red cards shown – 3;

Average fouls per match – 21;

Penalties – 18%.

Arsenal vs. Manchester City: Match Prediction

Despite the Citizens' low position in the table, this match will be the highlight of Matchday 5. In their last league game, both opponents secured convincing 3-0 victories, a clear indication that they have quickly bounced back from defeats and are in good spirits. Both clubs will be particularly motivated for this encounter, especially as Mikel Arteta faces his former boss Pep Guardiola.

Encounters between these rivals are rarely dull and low-scoring. Over the last decade, the teams have faced each other 20 times in the Premier League and have scored three or more goals against each other on 15 occasions. Additionally, such a number of goals has been recorded in 4 of Arsenal's last 5 home Premier League matches.

My prediction: Total over 2.5 goals

Arsenal vs Manchester City Odds

1X2
DOUBLE CHANCE
OVER/UNDER
BTTS
HANDICAP
TOTAL HOME GOALS
TOTAL AWAY GOALS

Current season

Logo Arsenal FC Logo Manchester City
3 Wins 2
1 Lost 2
2.25 GF per game 2
0.25 GA per game 1
5.5 Corners per game 4
1.75 Yellow cards per game 1.25

Premier League: previous matches of the tournament

Arsenal
09/13/25
Arsenal
Nottingham Forest
W
08/31/25
Liverpool
Arsenal
L
08/23/25
Arsenal
Leeds United
W
08/17/25
Manchester United
Arsenal
W
More games
Manchester City
09/14/25
Manchester City
Manchester United
W
08/31/25
Brighton and Hove Albion
Manchester City
L
08/23/25
Manchester City
Tottenham Hotspur
L
08/16/25
Wolverhampton Wanderers
Manchester City
W
More games

Head-to-Head: Arsenal — Manchester City

Premier League 2024-2025
02/02/25
Arsenal
Manchester City
09/22/24
Manchester City
Arsenal
Premier League 2023-2024
03/31/24
Manchester City
Arsenal
10/08/23
Arsenal
Manchester City
Super Cup England 2023
08/06/23
Manchester City
Arsenal
1
:
1
1
:
4
P
Premier League 2022-2023
04/26/23
Manchester City
Arsenal
02/15/23
Arsenal
Manchester City
FA Cup 2022-2023
01/27/23
Manchester City
Arsenal
Premier League 2021-2022
01/01/22
Arsenal
Manchester City
08/28/21
Manchester City
Arsenal
Premier League 2020-2021
02/21/21
Arsenal
Manchester City
10/17/20
Manchester City
Arsenal
FA Cup 2019-2020
07/18/20
Arsenal
Manchester City
Premier League 2019-2020
06/17/20
Manchester City
Arsenal
12/15/19
Arsenal
Manchester City
Premier League 2018-2019
02/03/19
Manchester City
Arsenal
08/12/18
Arsenal
Manchester City
Premier League 2017-2018
03/01/18
Arsenal
Manchester City
League Cup 2017-2018
02/25/18
Arsenal
Manchester City
0
:
3
Premier League 2017-2018
11/05/17
Manchester City
Arsenal
FA Cup 2016-2017
04/23/17
Arsenal
Manchester City
1
:
1
1
:
0
OT
Premier League 2016-2017
04/02/17
Arsenal
Manchester City
12/18/16
Manchester City
Arsenal
Premier League 2015-2016
05/08/16
Manchester City
Arsenal
12/21/15
Arsenal
Manchester City
Premier League 2014-2015
01/18/15
Manchester City
Arsenal
09/13/14
Arsenal
Manchester City
Premier League 2013-2014
03/28/14
Arsenal
Manchester City
1
:
1
12/13/13
Manchester City
Arsenal
6
:
3
Premier League 2012-2013
01/12/13
Arsenal
Manchester City
0
:
2
09/22/12
Manchester City
Arsenal
1
:
1
Premier League 2011-2012
04/07/12
Arsenal
Manchester City
1
:
0
12/17/11
Manchester City
Arsenal
1
:
0
Premier League 2010-2011
01/04/11
Arsenal
Manchester City
0
:
0
10/23/10
Manchester City
Arsenal
0
:
3
Premier League 2009-2010
04/23/10
Arsenal
Manchester City
0
:
0
09/11/09
Manchester City
Arsenal
4
:
2
Premier League 2008-2009
04/03/09
Arsenal
Manchester City
2
:
0
11/21/08
Manchester City
Arsenal
3
:
0
Premier League 2007-2008
02/01/08
Manchester City
Arsenal
1
:
3
08/24/07
Arsenal
Manchester City
1
:
0
Premier League 2006-2007
04/16/07
Arsenal
Manchester City
3
:
1
08/25/06
Manchester City
Arsenal
1
:
0
Premier League 2005-2006
05/03/06
Manchester City
Arsenal
1
:
3
10/21/05
Arsenal
Manchester City
1
:
0
Premier League 2004-2005
01/03/05
Arsenal
Manchester City
1
:
1
09/24/04
Manchester City
Arsenal
0
:
1
More games

Standings

Team Games W T L Goals Points Form
1
Liverpool
5 5 0 0 11:5 15
2
Tottenham Hotspur
5 3 1 1 10:3 10
3
Arsenal
4 3 0 1 9:1 9
4
Crystal Palace
5 2 3 0 6:2 9
5
Bournemouth
4 3 0 1 6:5 9
6
Chelsea
5 2 2 1 10:5 8
7
Fulham
5 2 2 1 6:5 8
8
Sunderland
4 2 1 1 5:3 7
9
Everton
5 2 1 2 6:5 7
10
Manchester United
5 2 1 2 6:8 7
11
Leeds United
5 2 1 2 4:7 7
12
Manchester City
4 2 0 2 8:4 6
13
Newcastle United
4 1 2 1 3:3 5
14
Brighton and Hove Albion
5 1 2 2 6:8 5
15
Nottingham Forest
5 1 2 2 5:9 5
16
Burnley
5 1 1 3 5:8 4
17
Brentford
5 1 1 3 6:10 4
18
West Ham United
5 1 0 4 5:13 3
19
Aston Villa
4 0 2 2 0:4 2
20
Wolverhampton Wanderers
5 0 0 5 3:12 0
Team Games W T L Goals Points Form
1
Liverpool
3 3 0 0 7:3 9
2
Fulham
3 2 1 0 5:2 7
3
Arsenal
2 2 0 0 8:0 6
4
Bournemouth
2 2 0 0 3:1 6
5
Sunderland
2 2 0 0 5:1 6
6
Manchester United
3 2 0 1 5:4 6
7
Brighton and Hove Albion
3 1 2 0 5:4 5
8
Chelsea
2 1 1 0 2:0 4
9
Everton
2 1 1 0 2:0 4
10
Leeds United
2 1 1 0 1:0 4
11
Burnley
3 1 1 1 3:2 4
12
Brentford
2 1 1 0 3:2 4
13
Tottenham Hotspur
2 1 0 1 3:1 3
14
Manchester City
2 1 0 1 3:2 3
15
Newcastle United
2 1 0 1 3:3 3
16
Nottingham Forest
2 1 0 1 3:4 3
17
Crystal Palace
2 0 2 0 1:1 2
18
Aston Villa
2 0 1 1 0:3 1
19
West Ham United
3 0 0 3 2:10 0
20
Wolverhampton Wanderers
3 0 0 3 3:10 0
Team Games W T L Goals Points Form
1
Tottenham Hotspur
3 2 1 0 7:2 7
2
Crystal Palace
3 2 1 0 5:1 7
3
Liverpool
2 2 0 0 4:2 6
4
Chelsea
3 1 1 1 8:5 4
5
Arsenal
2 1 0 1 1:1 3
6
Bournemouth
2 1 0 1 3:4 3
7
Everton
3 1 0 2 4:5 3
8
Leeds United
3 1 0 2 3:7 3
9
Manchester City
2 1 0 1 5:2 3
10
West Ham United
2 1 0 1 3:3 3
11
Newcastle United
2 0 2 0 0:0 2
12
Nottingham Forest
3 0 2 1 2:5 2
13
Fulham
2 0 1 1 1:3 1
14
Sunderland
2 0 1 1 0:2 1
15
Manchester United
2 0 1 1 1:4 1
16
Aston Villa
2 0 1 1 0:1 1
17
Brighton and Hove Albion
2 0 0 2 1:4 0
18
Burnley
2 0 0 2 2:6 0
19
Brentford
3 0 0 3 3:8 0
20
Wolverhampton Wanderers
2 0 0 2 0:2 0

Team Rosters

The line-ups will be known a few hours before kick-off
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