Serie A
Regular Season (16)
Cagliari
21 December
06:30
(EST)
Pisa

Cagliari vs Pisa: prediction & betting odds December 21, 2025

The Serie A Round 16 clash between Cagliari and Pisa will take place on December 21 at the Unipol Domus Stadium. Cagliari vs Pisa: prediction and betting odds, statistics.

Cagliari

In the last round, Fabio Pisacane's side were beaten 2-1 away by Atalanta. As a result, Cagliari have failed to win in 10 of their last 11 league matches (4 draws, 6 losses). The Sardinians have also kept a clean sheet in only 3 of their last 16 Serie A matches. Cagliari sit on 14 points and have slipped to 15th in the table.


  • The club has failed to win in 7 of their last 10 home Serie A matches (2 draws, 5 losses).
  • No more than two goals were scored in 5 of the last 7 home league games.
  • Cagliari scored more than once in only 3 of their last 10 home league matches.

Predicted Cagliari lineup (3-5-2)*

Elia Caprile – Gabriel Zappa, Juan Comeho, Sebastiano Luperto – Alessandro Deiola, Marco Palestra, Michael Folorunsho, Michel Adopo, Adam Obert – Gennaro Borrelli, Sebastiano Esposito.


Midfielder Mattia Felici and striker Andrea Belotti are unavailable due to injury. Additionally, forwards Joseph Lytetah and Zito Luvumbu have joined their national teams for the Africa Cup of Nations.

Pisa

Alberto Gilardino's side were beaten 1-0 away by Lecce in the last round. That was Pisa's third consecutive clean-sheet defeat in the league. The club have now failed to score in nine Serie A matches this season. Pisa sit second-bottom with 10 points. The team have scored only ten goals so far this campaign, the joint-worst tally in the division alongside Parma.


  • The team has not won in their last seven away league matches (4 draws, 3 losses).
  • At least one opponent failed to score in 8 of the club's last 11 Serie A matches.
  • Pisa failed to score in the first half in 12 of their last 13 league matches.

Predicted Pisa lineup (3-5-2)*

Adrian Semper – Simone Canestrelli, Antonio Caracciolo, Arturo Calabresi – Idrissa Touré, Isak Vural, Michel Ebišer, Mehdi Leris, Ebenezer Akinsanmiro – Henrik Meister, Stefano Moreo.


Midfielders Juan Cuadrado and Kelvin Stengs are sidelined through injury. Midfielder Ebenezer Akinsanmiro and forward Mbala Nzola have joined their national teams for the Africa Cup of Nations.

Referee

Francesco Furno (Italy)


Matches – 14 (Serie A, 2024/25–2025/26);

Yellow cards shown (including second yellows) – 60;

Average yellow cards per match – 4.3;

Red cards shown – 1;

Average fouls per match – 28;

Penalties – 29%.

Match prediction: Cagliari vs Pisa

Cagliari generally pick up more points at home. Backed by their supporters, the Sardinians look more confident on their own turf: this season they have taken eight points at home compared to six away. Overall, the club's home form is respectable — in their last eight home league matches they have lost just three times, with two of those defeats coming against Inter and Bologna.


Pisa have found life tough since promotion: they have recorded just one win in this Serie A campaign, which came at home against fellow newcomers Cremonese. On the road they are yet to win, picking up four draws and three defeats. In their latest away outing Pisa were beaten by a modest Lecce side.


I expect the hosts to put in a solid performance, and my prediction: Cagliari with handicap (0)


* Each team's predicted lineup is based on their most recent starting XI in this competition.

Cagliari vs Pisa Odds

1X2
DOUBLE CHANCE
OVER/UNDER
BTTS
TOTAL HOME GOALS
TOTAL AWAY GOALS
Bookie1X2

Serie A: previous matches of the tournament

Cagliari
12/13/25
Atalanta
Cagliari
L
12/07/25
Cagliari
AS Roma
W
11/29/25
Juventus
Cagliari
L
11/22/25
Cagliari
Genoa
T
11/08/25
Como
Cagliari
T
11/03/25
Lazio
Cagliari
L
10/30/25
Cagliari
Sassuolo
L
10/26/25
Hellas Verona
Cagliari
T
10/19/25
Cagliari
Bologna
L
10/05/25
Udinese
Cagliari
T
09/27/25
Cagliari
Inter Milan
L
09/19/25
Lecce
Cagliari
W
09/13/25
Cagliari
Parma
W
08/30/25
Napoli
Cagliari
L
08/24/25
Cagliari
Fiorentina
T
More games
Pisa
12/12/25
Lecce
Pisa
L
12/08/25
Pisa
Parma
L
11/30/25
Pisa
Inter Milan
L
11/24/25
Sassuolo
Pisa
T
11/07/25
Pisa
Cremonese
W
11/02/25
Torino
Pisa
T
10/30/25
Pisa
Lazio
T
10/24/25
AC Milan
Pisa
T
10/18/25
Pisa
Hellas Verona
T
10/05/25
Bologna
Pisa
L
09/28/25
Pisa
Fiorentina
T
09/22/25
Napoli
Pisa
L
09/14/25
Pisa
Udinese
L
08/30/25
Pisa
AS Roma
L
08/24/25
Atalanta
Pisa
T
More games

Standings

Team Games W T L Goals Points Form
1
Inter Milan
15 11 0 4 34:14 33
2
AC Milan
15 9 5 1 24:13 32
3
Napoli
15 10 1 4 22:13 31
4
AS Roma
15 10 0 5 16:8 30
5
Juventus
15 7 5 3 19:14 26
6
Bologna
15 7 4 4 23:13 25
7
Como
15 6 6 3 19:12 24
8
Lazio
15 6 4 5 17:11 22
9
Sassuolo
15 6 3 6 21:19 21
10
Udinese
15 6 3 6 16:22 21
11
Cremonese
15 5 5 5 18:18 20
12
Atalanta
15 4 7 4 19:18 19
13
Torino
15 4 5 6 15:26 17
14
Lecce
15 4 4 7 11:19 16
15
Cagliari
15 3 5 7 15:21 14
16
Genoa
15 3 5 7 16:23 14
17
Parma
15 3 5 7 10:18 14
18
Hellas Verona
15 2 6 7 13:22 12
19
Pisa
15 1 7 7 10:20 10
20
Fiorentina
15 0 6 9 12:26 6
Team Games W T L Goals Points Form
1
Napoli
7 6 1 0 14:6 19
2
Inter Milan
8 6 0 2 21:5 18
3
AC Milan
8 5 2 1 12:8 17
4
AS Roma
8 5 0 3 8:4 15
5
Juventus
7 4 3 0 12:6 15
6
Como
7 4 3 0 11:3 15
7
Lazio
7 4 2 1 13:5 14
8
Bologna
7 4 1 2 10:5 13
9
Atalanta
8 3 4 1 11:8 13
10
Udinese
8 3 2 3 8:12 11
11
Torino
8 3 2 3 9:14 11
12
Sassuolo
7 3 1 3 10:9 10
13
Cremonese
7 2 3 2 9:9 9
14
Lecce
8 2 3 3 6:8 9
15
Cagliari
7 2 2 3 8:10 8
16
Genoa
8 1 3 4 5:11 6
17
Parma
8 1 3 4 6:11 6
18
Hellas Verona
7 1 3 3 8:9 6
19
Pisa
8 1 3 4 1:5 6
20
Fiorentina
7 0 2 5 7:13 2
Team Games W T L Goals Points Form
1
Inter Milan
7 5 0 2 13:9 15
2
AC Milan
7 4 3 0 12:5 15
3
AS Roma
7 5 0 2 8:4 15
4
Napoli
8 4 0 4 8:7 12
5
Bologna
8 3 3 2 13:8 12
6
Juventus
8 3 2 3 7:8 11
7
Sassuolo
8 3 2 3 11:10 11
8
Cremonese
8 3 2 3 9:9 11
9
Udinese
7 3 1 3 8:10 10
10
Como
8 2 3 3 8:9 9
11
Lazio
8 2 2 4 4:6 8
12
Genoa
7 2 2 3 11:12 8
13
Parma
7 2 2 3 4:7 8
14
Lecce
7 2 1 4 5:11 7
15
Atalanta
7 1 3 3 8:10 6
16
Torino
7 1 3 3 6:12 6
17
Cagliari
8 1 3 4 7:11 6
18
Hellas Verona
8 1 3 4 5:13 6
19
Pisa
7 0 4 3 9:15 4
20
Fiorentina
8 0 4 4 5:13 4

Team Rosters

The line-ups will be known a few hours before kick-off
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