The Matchday 6 Serie A clash between Napoli and Genoa will take place on October 5 at the Diego Armando Maradona Stadium in Naples. Napoli vs. Genoa: prediction and betting odds, statistics.
Napoli
In the last round, Antonio Conte's side suffered a 2-1 away defeat to AC Milan. As a result, Napoli's 16-match unbeaten streak in the league (11 wins, 5 draws) came to an end. Additionally, the club conceded two goals in each of their last two Serie A matches. Consequently, Napoli lost their lead in the standings, dropping to second place. Notably, they are the only team in the current championship to have taken maximum points at home (six points in two games).
- The club has won 7 of their last 8 home matches in Serie A.
- The team has scored at least two goals in 7 of their last 8 home league matches.
- Exactly 2 or 3 goals have been scored in 9 of Napoli's last 12 home Serie A games.
Predicted lineup for Napoli (3-5-2)
Vanja Milinkovic-Savic – Miguel Gutierrez, Juan Jesus, Sam Beukema – Leonardo Spinazzola, Kevin De Bruyne, Stanislav Lobotka, Andre-Frank Zambo Anguissa, Scott McTominay – Rasmus Hojlund, Matteo Politano.
Defenders Amir Rrahmani, Alessandro Buongiorno, and forward Romelu Lukaku will miss the match due to injuries. Defender Mathias Olivera's participation is doubtful.
Genoa
Patrick Vieira's side could not put up a fight against Lazio at home in the last round (0-3). As a result, Genoa suffered their first major defeat in Serie A in 2025 and extended their winless streak in the league to five matches (2 draws, 3 losses). Furthermore, the team failed to score for the third time in this Serie A campaign. In the standings, Genoa sits second to last with two points.
- The club has not won in 12 of their last 13 away Serie A matches (6 draws, 6 losses).
- The team has conceded exactly 1 or 2 goals in 10 of their last 11 away league matches.
- No more than two goals have been scored in 7 of Genoa's last 10 away Serie A games.
Predicted lineup for Genoa (4-5-1)
Nicola Leali – Brooke Norton-Cuffy, Leo Ostigard, Johan Vasquez, Aaron Martin Caricol – Vitinha, Morten Frendrup, Ruslan Malinovskyi, Patrizio Masini, Mikael Ellertsson – Lorenzo Colombo.
Midfielder Jean Onana will miss the match due to injury.
Referee
Federico La Penna (Italy)
Matches – 16 (Serie A, 2024/25–2025/26);
Yellow cards shown (including second yellows) – 63;
Average yellow cards per match – 3.9;
Red cards shown – 1;
Average fouls per match – 27;
Penalties – 31%.
Napoli vs. Genoa: Match Prediction
At home, Napoli feels confident and tends to play from a position of strength, focusing as much as possible on attack. This style of play allows the team to score frequently: in their last eight home Serie A matches, Napoli has only once failed to score more than one goal. However, the team has lost its former defensive reliability, conceding four goals in the last two league rounds.
Genoa has recently increased their scoring in away matches: in their last four Serie A games, the team has not left the field without finding the net. Moreover, they have scored seven goals during this period. However, in their last 12 away league encounters, the club has only kept a clean sheet once, and in the current Serie A campaign, Genoa has already conceded seven goals, surpassing only two teams in this regard.
I expect a high-scoring encounter, so my prediction: Total over 2 goals
